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ChemicalBook--->CAS DataBase List--->72252-96-1

72252-96-1

72252-96-1 Structure

72252-96-1 Structure
IdentificationBack Directory
[Name]

N-succinimidyl-4-((iodoacetyl)amino)benzoate
[CAS]

72252-96-1
[Synonyms]

N-succinimidyl-(4-iodoacetamido)benzoate
4-[(2-Iodoacetyl)aMino]benzoic Acid 2,5-dioxo-1-pyrrolidinyl Ester
N-[4-[[(2,5-Dioxopyrrolidin-1-yl)oxy]carbonyl]phenyl]-2-iodoacetamide
[Molecular Formula]

C13H11IN2O5
[MDL Number]

MFCD00078537
[MOL File]

72252-96-1.mol
[Molecular Weight]

402.14
Chemical PropertiesBack Directory
[Melting point ]

19-7-200°C (dec.)
[density ]

1.87±0.1 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under Inert Atmosphere
[solubility ]

Acetontrile (Slightly), DMSO (Slightly)
[form ]

Solid
[pka]

12.16±0.70(Predicted)
[color ]

Pale Yellow
Hazard InformationBack Directory
[Chemical Properties]

Pale Yellow Solid
[Uses]

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 10.6 Angstroms
[General Description]

SIAB is an amine- and sulfhydryl-reactive heterobifunctional crosslinker and Sulfo-SIAB is its water-soluble analog. These crosslinkers contain an amine-reactive N-hydroxysuccimide (NHS) ester and a sulfhydryl-reactive iodoacetyl group, and are often used for preparing enzyme conjugates or immunotoxins. Water-soluble and water-insoluble forms of NHS esters have essentially identical reactivity. Sulfo-SIAB is supplied as a sodium salt and is water-soluble to ~10mM. SIAB must be first dissolved in an organic solvent, such as DMSO or DMF, and then added to the aqueous reaction mixture. SIAB is lipophilic, membrane-permeable and does not possess a charged group.
[reaction suitability]

reagent type: cross-linking reagent
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P280-P302+P352-P304+P340-P305+P351+P338-P312-P321
[HS Code ]

2921490090
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