| Identification | Back Directory | [Name]
SH-5 | [CAS]
701976-54-7 | [Synonyms]
SH-5
PIA 5
AKT INHIBITOR II
D-3-DEOXY-2-O-METHYL-MYO-INOSITOL 1-[(R)-2-METHOXY-3-(OCTADECYLOXY)PROPYL HYDROGEN PHOSPHATE]
1-Deoxy-6-O-methyl-L-chiro-inositol 5-[(2R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate]
L-chiro-Inositol, 1-deoxy-6-O-methyl-, 5-[(2R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate]
SH5 PIA5. LchiroInositol 1deoxy6Omethyl 5(2R)2methoxy3(octadecyloxy)propyl hydrogen phosphate. Akt inhibitor II | [Molecular Formula]
C29H59O10P | [MDL Number]
MFCD08703608 | [MOL File]
701976-54-7.mol | [Molecular Weight]
598.75 |
| Hazard Information | Back Directory | [Biological Activity]
Cell permeable: yes''Primary Target
Akt''Product does not compete with ATP.''Reversible: yes | [Enzyme inhibitor]
This phosphatidylinositol analogue (FWfree-acid = 598.76 g/mol), also known as SH-5, inhibits the proto-oncogenic serine/threonine kinase Akt (protein kinase B), inducing apoptosis. Specific inhibition of Akt by these compounds validates ligand design targeted to the PH domains of crucial signaling proteins, thus providing a unique class of possible cancer therapeutics. |
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| Company Name: |
Carbosynth
|
| Tel: |
+86 512 6260 5585 |
| Website: |
www.carbosynth.com |
| Company Name: |
Abcam
|
| Tel: |
+1 (877) 774-8286 |
| Website: |
www.abcam.com |
|