| Identification | Back Directory | [Name]
6,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID, SODIUM SALT | [CAS]
68324-96-9 | [Synonyms]
Prostaglandin I3 (sodium)
JYCZBBNTGSRZMY-YICKWJRGSA-M
PROSTAGLANDIN I3 SODIUM SALT
Prostaglandin I3 (sodium salt) Exclusive
6,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROSTA-5Z,13E,17Z-TRIEN-1-OIC ACID, SODIUM SALT | [Molecular Formula]
C20H29NaO5 | [MDL Number]
MFCD00216080 | [MOL File]
68324-96-9.mol | [Molecular Weight]
372.43 |
| Hazard Information | Back Directory | [Description]
PGI3 is synthesized from EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to Δ17-6-keto PGF1α. The platelet and vascular activity of PGI3 is equivalent to that of PGI2.1,2 | [References]
1. Mann, N.J., Warrick, G.E., O'Dea, K., et al. The effect of linoleic, arachidonic, and eicosapentaenoic acid supplementation of prostacyclin production in rats Lipids 29(3),157-162(1994).
2. Johnson, R.A., Lincoln, F.H., Nidy, E.G., et al. Synthesis and characterization of prostacyclin, 6-ketoprostaglandin F1α, prostaglandin I1, and prostaglandin I3 J. Am. Chem. Soc. 100(24),7690-7704(1978). |
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