| Identification | Back Directory | [Name]
ubiquitin cross-reactive protein | [CAS]
60267-61-0 | [Synonyms]
C00496
Ubiquitin-13C,15N human
ubiquitin cross-reactive protein
Ubiquitin-13C,15N human >=98 atom %, >=90% (CP), recombinant, expressed in E. coli |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
Tris-HCl, pH 7.5: 1.0—1.10mg/mL, clear to slightly hazy, colorless | [form ]
saline suspension | [biological source]
human |
| Hazard Information | Back Directory | [Uses]
Ubiquitin, N-terminal FLAG-tagged can replace the ubiquitin in formation of poly-ubiquitin—protein conjugates. The FLAG tag enables separation and enrichment of the protein conjugates on anti-FLAG affinity columns and detection of conjugates in western blot by anti-FLAG antibodies. | [General Description]
Ubiquitin, a globular protein is made of 76 amino acids and has lysine residues on its surface. It has a molecular weight of 8565 Da. | [Biochem/physiol Actions]
Ubiquitin interacts with the lysine residue of proteins through its ε-amino group of the C-terminal glycine residue. Proteins interacting with ubiquitin either undergo mono-ubiquitination or multi-mono-ubiquitination via a three-step process. Ubiquitination regulates intracellular trafficking and protein degradation and an imbalance in the pathway is implicated in disorders. |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|