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ChemicalBook--->CAS DataBase List--->6011-12-7

6011-12-7

6011-12-7 Structure

6011-12-7 Structure
IdentificationBack Directory
[Name]

Ambazone hydrate
[CAS]

6011-12-7
[Synonyms]

Iversal
Unii-byk4592A3q
Ambazone hydrate
Ambazone-1-hydrate
Ambazone Monohydrate
1,4-Benzoquinone guanylhydrazone thiosemicarbazone hydrate
[Molecular Formula]

C8H13N7OS
[MDL Number]

MFCD00884658
[MOL File]

6011-12-7.mol
[Molecular Weight]

255.3
Chemical PropertiesBack Directory
[Melting point ]

188 °C (decomp)(Solv: water (7732-18-5); ammonia (7664-41-7))
Hazard InformationBack Directory
[Originator]

Ambazone,Generic
[Manufacturing Process]

To a solution of 22.7 g of quinone monoguanylhydrazone nitrate in 250 ml water is added dropwise hot aqueous solution of 9.1 g thiosemicarbazide, then is added slowly a solution of 5 ml concentrated nitric acid in 10 ml of water. The mixture is stirred at 60°C for 1 hour. The product is dissolved in 1-1.2 L of water at 100°C. The solution is filtered and added to an aqueous ammonium solution. Blue residue of p-benzoquinone amidinohydrazone thiosemicarbazone is filtered and dried, melting point 188°C (decomp.).
[Therapeutic Function]

Antiseptic
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