| Identification | Back Directory | [Name]
8-ETHYL-1,4,7,8-TETRAHYDRO-4-METHYL-2-(2,3,5-TRICHLOROPHENYL)-5H-IMIDAZO[2,1-I]PURIN-5-ONE MONOHYDROCHLORIDE | [CAS]
591771-91-4 | [Synonyms]
PSB 10
PSB 10 HYDROCHLORIDE
8-ETHYL-1,4,7,8-TETRAHYDRO-4-METHYL-2-(2,3,5-TRICHLOROPHENYL)-5H-IMIDAZO[2,1-I]PURIN-5-ONE MONOHYDROCHLORIDE | [Molecular Formula]
C16H14Cl3N5O.ClH | [MDL Number]
MFCD08703091 | [MOL File]
591771-91-4.mol | [Molecular Weight]
435.141 |
| Hazard Information | Back Directory | [Biological Activity]
Potent and highly selective antagonist for the human adenosine A 3 receptor, with low affinity for the rat A 3 receptor (K i values are 0.44 and > 17000 nM respectively). Displays > 3800-fold selectivity over human A 1 , A 2A and A 2B receptors (K i values are 4.1, 3.3 and 30 μ M respectively) and > 1800-fold selectivity over rat A 1 and A 2A receptors. Acts as an inverse agonist in the [ 35 S]GTP γ S binding assay in hA 3 -CHO cells (IC 50 = 4 nM). Produces thermal hyperalgesia in mice in vivo . | [storage]
Desiccate at +4°C |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
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