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ChemicalBook--->CAS DataBase List--->577-38-8

577-38-8

577-38-8 Structure

577-38-8 Structure
IdentificationBack Directory
[Name]

FLAVANOMAREIN
[CAS]

577-38-8
[Synonyms]

FLAVANOMAREIN
FLAVANOMAREIN hplc
TRIHYDROXYFLAVANONE
ISOOKANIN-7-GLUCOSIDE
ISOOKANIN-7-O-GLUCOSIDE
FLAVANOMAREIN WITH HPLC
FLAVANOMAREIN USP/EP/BP
7-O-GLUCOSYL-4',5',8-TRIHYDROXYFLAVANONE
3',4',7,8-TETRAHYDROXYFLAVANONE-7-O-GLUCOSIDE
(S)-2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one
(S)-2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-, (2S)-
(2S)-2-(3,4-dihydroxyphenyl)-8-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-chroman-4-one
(2S)-2-(3,4-dihydroxyphenyl)-8-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one
[EINECS(EC#)]

209-411-1
[Molecular Formula]

C21H22O11
[MDL Number]

MFCD00136058
[MOL File]

577-38-8.mol
[Molecular Weight]

450.39
Chemical PropertiesBack Directory
[Melting point ]

243-246°C
[Boiling point ]

818.2±65.0 °C(Predicted)
[density ]

1.665±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

7.58±0.40(Predicted)
[color ]

White to off-white
[LogP]

-1.080 (est)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P271
[Hazard Codes ]

Xi
Hazard InformationBack Directory
[Chemical Properties]

Flavanomarein, known as isookanin-7-o-glucoside, is a dihydroflavonoid isolated from the ethanolic extract of Coreopsistinctoria and is considered to be one of the active ingredients of the herb with a wide range of pharmacological effects, but there are not many studies on the in vitro and in vivo pharmacokinetics of flavanomarein.
[Uses]

Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities.
Flavanomarein inhibits high glucose-stimulated epithelialmesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase
Spectrum DetailBack Directory
[Spectrum Detail]

Flavanomarein(577-38-8)1HNMR
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