Identification | Back Directory | [Name]
(Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester | [CAS]
56687-85-5 | [Synonyms]
(+)-Cloprostenol methyl ester (+)-Cloprostenol methyl ester Exclusive (+)Cloprostenol methyl ester,(+) Cloprostenol methyl ester (5Z,9S,11R,13E,15R)-9,11,15-Trihydroxy-16-(3-chlorophenoxy)-17,18,19,20-tetranorprosta-5,13-diene-1-oic acid methyl ester (Z)-7-[2β-[(1E,3R)-3-Hydroxy-4-(3-chlorophenoxy)-1-butenyl]-3α,5α-dihydroxycyclopentane-1α-yl]-5-heptenoic acid methyl ester (Z)-7-[(1R)-2β-[(E,R)-4-(3-Chlorophenoxy)-3-hydroxy-1-butenyl]-3α,5α-dihydroxycyclopentan-1α-yl]-5-heptenoic acid methyl ester 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-, methyl ester, (5Z)- | [Molecular Formula]
C23H31ClO6 | [MDL Number]
MFCD01723695 | [MOL File]
56687-85-5.mol | [Molecular Weight]
438.94 |
Chemical Properties | Back Directory | [Boiling point ]
585.5±50.0 °C(Predicted) | [density ]
1.264±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 50 mg/ml; DMSO: 100 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): 10 mg/ml | [pka]
13.41±0.20(Predicted) |
Hazard Information | Back Directory | [Description]
(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. It is 200 times and 100 times more potent than PGF2α in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with PGF2α. Cloprostenol is also used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (+)-Cloprostenol methyl ester is a more lipid soluble form of cloprostenol, which may be more amenable for certain formulations. |
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