| Identification | Back Directory | [Name]
1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE | [CAS]
547756-93-4 | [Synonyms]
JTE 013
1-(3,5-Dichloropyridin-4-yl)-3-[(1,3-dimethyl-4-propylpyrazolo[3,4-b]pyridin-6-yl)amino]urea
N-(2,6-Dichloropyridin-4-yl)-2-(4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-6-yl)hydrazinecarboxamide
1-[1,3-DIMETHYL-4-(2-METHYLETHYL)-1H-PYRAZOLO[3,4-B]PYRIDIN-6-YL]-4-(3,5-DICHLORO-4-PYRIDINYL)-SEMICARBAZIDE | [Molecular Formula]
C17H19Cl2N7O | [MDL Number]
MFCD08703118 | [MOL File]
547756-93-4.mol | [Molecular Weight]
408.285 |
| Hazard Information | Back Directory | [Uses]
JTE 013 is an antagonist of Sphingosine-1-Phosphate Receptor-2 (S1P2R). | [Biological Activity]
Sphingosine-1-phosphate (S1P) receptor antagonist, highly selective for S1P 2 (EDG-5). Inhibits S1P binding to human S1P 2 receptors with an IC 50 value of 17.6 nM. At concentrations up to 10 μ M, displays 4.2% inhibition of S1P 3 and does not antagonize S1P 1 . Enhances S1P-induced angiogenesis in vivo . |
|
| Company Name: |
|
| Tel: |
821-50328103-801 18930552037 |
| Website: |
http://www.yuhua99.com/ShowSupplierProductsList13285/0.htm |
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
amyjetsci
|
| Tel: |
027-59626688 18771149750 |
| Website: |
https://www.amyjet.com/ |
| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
|