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ChemicalBook--->CAS DataBase List--->4999-79-5

4999-79-5

4999-79-5 Structure

4999-79-5 Structure
IdentificationBack Directory
[Name]

17β-Estradiol 3-O-Sulfate SodiuM Salt
[CAS]

4999-79-5
[Synonyms]

17β-Estradiol sodium sulfate
17β-Estradiol sulfate sodium
17β-Estradiol 3-sulfate sodium
SODIUM 17B-ESTRADIOL 3-SULFATE
17B-estradiol 3-sulfate sodium
b-Estradiol 3-sulfate sodium salt
oestradiol 3-sulfate, sodium salt
17BETA-ESTRADIOL 3-SULFATE SODIUM
17-Beta-Estradiol-3-O-Sulfate SodiuM
17β-Estradiol 3-Sulphate Sodium Salt
β-Estradiol 3-sulfate sodium salt
17β-Estradiol 3-Sulphate, Sodium Salt
17β-Estradiol 3-O-Sulfate Sodium Salt
17β-Estradiol 3-O-Sulfate Sodium Salt
17BETA-ESTRADIOL 3-SULFATE SODIUM SALT
17-BETA-ESTRADIOL 3-SULPHATE, SODIUM SALT
1,3,5(10)-Estratriene-3,17β-diol 3-sulfate
3,17β-Dihydroxy-1,3,5(10)-estratriene 3-sulfate
1,3,5(10)-ESTRATRIEN-3,17BETA-DIOL 3-SULFATE SODIUM
1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 3-SULFATE SODIUM SALT
1, 3, 5(10)-ESTRATRIEN-3, 17β-DIOL 3-SULPHATE, SODIUM SALT
1,3,5(10)-ESTRATRIEN-3,17-BETA-DIOL 3-SULPHATE, SODIUM SALT
17β-Estradiol 3-sulfate sodium|||17β-Estradiol sulfate sodium
3,17BETA-DIHYDROXY-1,3,5[10]-ESTRATRIENE 3-SULFATE SODIUM SALT
Estra-1,3,5(10)-triene-3,17-diol(17b)-, 3-(hydrogen sulfate), sodiumsalt (1:1)
1,3,5(10)-Estratriene-3,17β-diol 3-sulfate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-sulfate
[Molecular Formula]

C18H23NaO5S
[MDL Number]

MFCD00056553
[MOL File]

4999-79-5.mol
[Molecular Weight]

374.43
Chemical PropertiesBack Directory
[Melting point ]

207 °C
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly), Water (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Stability:]

Hygroscopic
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

20/21/22-40
[Safety Statements ]

22-36
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

17β-Estradiol 3-O-Sulfate Sodium Salt is a neuroactive steroid used in the studies of human recombinant p1 γ-aminobutyric acid type C (GABAC) recptors.
[Uses]

β-Estradiol 3-sulfate sodium salt has been used to measure the estradiol level from culture supernatant in ultra-performance liquid chromatography-tandem mass spectrometry.
[General Description]

β-Estradiol is secreted by developing ovaries and is predominant during premenopause in women.
[Biochem/physiol Actions]

β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, hence it is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.
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