| Identification | Back Directory | [Name]
PROSTAGLANDIN BX | [CAS]
39306-29-1 | [Synonyms]
pgbx
PROSTAGLANDIN BX
prostaglandinbx,sodiumsalt
Prostaglandin Bx Exclusive | [Molecular Formula]
C20H32O4 | [MDL Number]
MFCD00071377 | [MOL File]
39306-29-1.mol | [Molecular Weight]
336.466 |
| Hazard Information | Back Directory | [Definition]
ChEBI: Prostaglandin B1 is a member of the class of prostaglandins B that is prosta-8(12),13-dien-1-oic acid carrying oxo and hydroxy substituents at positions 9 and 15 respectively (the 13E,15S-stereoisomer). It has a role as a human metabolite. It is a conjugate acid of a prostaglandin B1(1-). | [Enzyme inhibitor]
This eicosanoid (FWB1 (free-acid) = 336.47 g/mol; CAS 13345-51-2, for PGB1, and 39306-29-1, for Bx) is a metabolite of prostaglandin E1: prostaglandin Bx is an oligomer of prostaglandin B1. The X-ray crystal structure of prostaglandin B1 suggests this prostaglandin has an unusual L-shaped configuration, with the a and w side chains roughly perpendicular to one another. The 15-hydroxyl group, which is normally directed away from the centroid of the prostaglandin in the standard hairpin mod+el, is turned inward in prostaglandin B1. Target (s) : FoF1 ATPase, or H-transporting two-sector ATPase, inhibited by prostaglandin Bx; 15- hydroxyprostaglandin dehydrogenase; phospholipase A2, inhibited by prostaglandin Bx. |
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