| Identification | Back Directory | [Name]
Emodin 6-O-β-D-glucoside | [CAS]
34298-85-6 | [Synonyms]
Glucoemodin
Emodin-6-O-glucoside
Emodin 6-O-β-D-glucoside
Emodin 6-O-β-D-glucoside
Emodin-6-O-glucopyranoside
Emodin 6-O-beta-D-glucoside
emodin-6-O-β-D-glucopyranoside
9,10-Anthracenedione, 3-(β-D-glucopyranosyloxy)-1,8-dihydroxy-6-methyl- | [Molecular Formula]
C21 H20 O10 | [MDL Number]
MFCD29036622 | [MOL File]
34298-85-6.mol | [Molecular Weight]
432.38 |
| Chemical Properties | Back Directory | [Melting point ]
176-178 °C | [Boiling point ]
801.9±65.0 °C(Predicted) | [density ]
1.667±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
5.99±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Emodin-6-O-β-D-glucoside (Glucoemodin) is an active compound from Reynoutria japonica. Emodin-6-O-β-D-glucoside shows potent anti-inflammatory and barrier protective effects. Emodin-6-O-β-D-glucoside can be used for the research of diabetic complications and atherosclerosis[1]. | [in vivo]
Emodin-6-O-β-D-glucoside (0~9 mg/mouse; i.v.) markly inhibits peritoneal leakage of dye induced by high glucose[1]. | Animal Model: | Mouse[1] | | Dosage: | 0~9 mg/mouse | | Administration: | I.v. | | Result: | Markly inhibited peritoneal leakage of dye induced by high glucose.
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| [References]
[1] Lee W, et al. Emodin-6-O-β-D--glucoside inhibits high-glucose-induced vascular inflammation. Inflammation. 2014;37(2):306-313. DOI:10.1007/s10753-013-9741-9 |
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