| Identification | Back Directory | [Name]
4-HYDROXYESTRONE | [CAS]
3131-23-5 | [Synonyms]
4-OH-E1
4-HYDROXYESTRONE
1,3,5(10)-ESTRATRIEN-3,4-DIOL-17-ONE
1,3,5[10]-ESTRATRIENE-3,4-DIOL-17-ONE
5(10)-trien-17-one,3,4-dihydroxy-estra-3
3,4-DIHYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE
3,4-dihydroxyestra-1,3,5(10)-trien-17-one
3,4-Dihydroxy-1(10),2,4-estratriene-17-one
3,4-Dihydroxyestra-1(10),2,4-triene-17-one
(9S,14S)-3,4-dihydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one | [Molecular Formula]
C18H22O3 | [MDL Number]
MFCD00079358 | [MOL File]
3131-23-5.mol | [Molecular Weight]
286.37 |
| Chemical Properties | Back Directory | [Appearance]
Pale Yellow Solid | [Melting point ]
260-263°C | [Boiling point ]
468.2±45.0 °C(Predicted) | [density ]
1.241±0.06 g/cm3(Predicted) | [Fp ]
93 °C | [storage temp. ]
−20°C
| [solubility ]
DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly) | [form ]
Solid | [pka]
10.06±0.40(Predicted) | [color ]
Pale Yellow to Light Brown |
| Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow Solid | [Uses]
A metabolite of Estradiol | [Definition]
ChEBI: A 4-hydroxy steroid that is estrone substituted by a hydroxy group at position 4. | [Hazard]
A reproductive hazard. | [Biochem/physiol Actions]
4-Hydroxyestrone is an endogenous estrogen metabolite, which exhibits a strong neuroprotective effect against oxidative damage. It also provides effective protection against kanic acid-induced hippocampal oxidative damage in rats when compared to 17β-estradiol. 4-Hydroxyestrone regulates the angiogenic process during corpus luteum formation. It might be involved in an increased risk of cancer. 4-Hydroxyestrone is found in the early and mid-luteal phases. |
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Sigma-Aldrich
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| Company Name: |
Energy Chemical
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http://www.energy-chemical.com |
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