| Identification | Back Directory | [Name]
5-(5-{[1-(3-carboxyphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]methyl}-2-furyl)-2-chlorobenzoic acid | [CAS]
292065-64-6 | [Synonyms]
X80
TDRL-X80
X80 >=98% (HPLC)
5-(5-{[1-(3-carboxyphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]methyl}-2-furyl)-2-chlorobenzoic acid
Benzoic acid, 5-[5-[[1-(3-carboxyphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]methyl]-2-furanyl]-2-chloro- | [Molecular Formula]
C23H15ClN2O6 | [MDL Number]
MFCD02086439 | [MOL File]
292065-64-6.mol | [Molecular Weight]
450.83 |
| Hazard Information | Back Directory | [Uses]
X80 has been used as an inhibitor of nucleotide excision repair (NER) pathway to study its effects on 8-hydroxy-2μ-deoxyguanosine (8-OHdG) excision in the zygote post-fertilization. | [Biological Activity]
X80 is an inhibitor of xeroderma pigmentosum group A protein (XPA protein) required for the removal of all types of DNA lesions repaired by nucleotide excision repair Including both transcription coupled and global genomic nucleotide excision repair. |
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Energy Chemical
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http://www.energy-chemical.com |
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