| Identification | Back Directory | [Name]
L-DICENTRINE | [CAS]
28832-07-7 | [Synonyms]
Eximine
(R)-forM
NSC251699
NSC-251699
NSC 251699
L-DICENTRINE
(R)-(-)-DICENTRINE
Cepharanthine α-base
9,10-DiMethoxy-1,2-(Methylenedioxy)-6aβ-aporphine
(R)-6,7,7a,8-Tetrahydro-10,11-diMethoxy-7-Methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quin
10,11-Dimethoxy-7-methyl-6,7,7A,8-tetrahydro-5H-benzo[G][1,3]benzodioxolo[6,5,4-de]quinoline
5H-Benzo[G]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7A,8-tetrahydro-10,11-dimethoxy-7-methyl-
(7aR)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline
5H-Benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7a,8-tetrahydro-10,11-dimethoxy-7-methyl-, (7aR)-
Inchi=1/C20H21no4/C1-21-5-4-11-7-17-20(25-10-24-17)19-13-9-16(23-3)15(22-2)8-12(13)6-14(21)18(11)19/H7-9,14H,4-6,10H2,1-3h | [Molecular Formula]
C20H21NO4 | [MDL Number]
MFCD00210492 | [MOL File]
28832-07-7.mol | [Molecular Weight]
339.39 |
| Chemical Properties | Back Directory | [Boiling point ]
480.7±45.0 °C(Predicted) | [density ]
1.266±0.06 g/cm3 (20 ºC 760 Torr) | [form ]
Solid | [pka]
6.65±0.20(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
A natural vascular alpha 1-adrenoceptor antagonist but less prevalent than the D-isomer. It markedly inhibits the contraction of rat stomach muscle strips induced by 5-HT, histamine, K+ and Ca2+ after high K+ depolarization, showing a non-competitive antagonism and could be a potential muscle relaxant. Studies suggest that it has protective effect of on acute myocardial Iichemia and anoxia lesion. |
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