| Identification | Back Directory | [Name]
Pyrido[2,3-d]pyrimidin-2(1H)-one, 1-[4-(dimethylphosphinyl)-2-methyl-6-(1-methylethyl)phenyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]- | [CAS]
2649004-88-4 | [Synonyms]
Pyrido[2,3-d]pyrimidin-2(1H)-one, 1-[4-(dimethylphosphinyl)-2-methyl-6-(1-methylethyl)phenyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]- | [Molecular Formula]
C33H36F2N5O4P | [MOL File]
2649004-88-4.mol | [Molecular Weight]
635.64 |
| Chemical Properties | Back Directory | [Boiling point ]
826.8±75.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
6.52±0.35(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
KRAS G12C inhibitor 28 is a KRAS G12C inhibitor with an IC50 of 57 nM. KRAS G12C inhibitor 28 has antitumor effects (WO2021113595A1; Example 1)[1]. |
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