| Identification | Back Directory | [Name]
Anamorelin | [CAS]
249921-19-5 | [Synonyms]
CS-896
Rc 1291
ONO-7643
Anamoelin
anamorelin
Unii-dd5rba1nkf
Anamorelin (RC-1291)
Anamorelin intemediate
Anamorelin (ONO 7643)
Anamorelin(ONO-7643,RC-129)
RC-1291; ONO-7643; RC1291; ONO7643; RC 1291; ONO 7643
5H-Pyrrolo[1,2-a]imidazole-2-carboxaldehyde,6,7-dihydro-(10CI)
3-Piperidinecarboxylic acid, 1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-, trimethylhydrazide, (3R)-
(3R)-1-(2-Methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide
(R)-1-((S)-2-((1H-indol-3-yl)methyl)-5-amino-5-methyl-4-oxohexanoyl)-3-benzyl-N,N',N'-trimethylpiperidine-3-carbohydrazide
2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-[dimethylamino(methyl)carbamoyl]piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-methylpropanamide
3-Piperidinecarboxylic acid, 1-[(2R)-2-[(2-amino-2-methyl-1-oxopropyl)amino]-3-(1H-indol-3-yl)-1-oxopropyl]-3-(phenylmethyl)-, 1,2,2-trimethylhydrazide, (3R)- | [Molecular Formula]
C31H42N6O3 | [MDL Number]
MFCD11973671 | [MOL File]
249921-19-5.mol | [Molecular Weight]
546.7 |
| Chemical Properties | Back Directory | [Melting point ]
132-134°C | [density ]
1.214 | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
16.22±0.46(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
Anamorelin functions as a novel therapeutic options for cachexia and sarcopenia. Cancer cachexia and clinical therapeutic interventions. | [Biological Activity]
Anamorelin is a non-peptidic ghrelin mimetic and growth hormone (GH) secretagogue. It is an orally-activebrain-penetrantselective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR). Anamorelin has been shown to increases appetiteoverall body weightlean body massand muscle strength in clinical studies with cancer patients suffering from cachexia. | [storage]
Store at -20°C |
|
|