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ChemicalBook--->CAS DataBase List--->2471967-92-5

2471967-92-5

2471967-92-5 Structure

2471967-92-5 Structure
IdentificationBack Directory
[Name]

1,6-Naphthyridine-6(5H)-carboxamide, N-[2-(4-fluorophenoxy)-5-pyrimidinyl]-5-(4-fluorophenyl)-7,8-dihydro-, (5S)-
[CAS]

2471967-92-5
[Synonyms]

BAY-899
1,6-Naphthyridine-6(5H)-carboxamide, N-[2-(4-fluorophenoxy)-5-pyrimidinyl]-5-(4-fluorophenyl)-7,8-dihydro-, (5S)-
[Molecular Formula]

C25H19F2N5O2
[MDL Number]

MFCD32263051
[MOL File]

2471967-92-5.mol
[Molecular Weight]

459.45
Chemical PropertiesBack Directory
[density ]

1.397±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: 1mg/mL, clear
[form ]

Solid
[pka]

12.52±0.40(Predicted)
[color ]

White to off-white
[optical activity]

[α]/D 165 to 195°, c =1 in chloroform-d
Hazard InformationBack Directory
[Biological Activity]

BAY-899 is an orally availablepotent and selective antagonist of the human luteinizing hormone receptor (hLH-R) th at reduces sex hormone levels in several animal models. BAY-899 likely binds to a putative rhodopsin-like binding cavity located within the 7-transmembrane region of the hLH-receptor.
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