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ChemicalBook--->CAS DataBase List--->2375554-02-0

2375554-02-0

2375554-02-0 Structure

2375554-02-0 Structure
IdentificationBack Directory
[Name]

Senexin C
[CAS]

2375554-02-0
[Synonyms]

Senexin C
[Molecular Formula]

C28H27N5O
[MOL File]

2375554-02-0.mol
[Molecular Weight]

449.56
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Description]

Senexin C exhibits potent CDK8/19 inhibitory activity with high selectivity. Senexin C is more metabolically stable and provides a more sustained inhibition of CDK8/19-dependent cellular gene expression when compared with the prototype inhibitor Senexin B. Senexin C inhibits MV4-11 leukemia growth in a systemic in vivo model with good tolerability.
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