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ChemicalBook--->CAS DataBase List--->2354405-14-2

2354405-14-2

2354405-14-2 Structure

2354405-14-2 Structure
IdentificationBack Directory
[Name]

FAK inhibitor 2
[CAS]

2354405-14-2
[Synonyms]

FAK inhibitor 2
[Molecular Formula]

C29H33F3N8O2S2
[MDL Number]

MFCD32067961
[MOL File]

2354405-14-2.mol
[Molecular Weight]

646.75
Chemical PropertiesBack Directory
[density ]

1.382±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

14.57±0.46(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

FAK inhibitor 2 is a potent focal adhesion kinase (FAK) inhibitor with an IC50 ?of 0.07?nM, with antitumor and anti-angiogenesis activities[1]. IC50: 0.07?nM (FAK)[1]

[References]

[1]. Su Y, et al. Discovery of 2,4-diarylaminopyrimidine derivatives bearing dithiocarbamate moiety as novel FAK inhibitors with antitumor and anti-angiogenesis activities. Eur J Med Chem. 2019 May 18;177:32-46.

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