| Identification | Back Directory | [Name]
BRD-IN-3 | [CAS]
2351938-32-2 | [Synonyms]
BRD-IN-3
BRD IN 3,BRDIN3
4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-[[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-3-piperidinyl]amino]-3,5-dihydro-3-methyl- | [Molecular Formula]
C21H25N5O3 | [MDL Number]
MFCD32067976 | [MOL File]
2351938-32-2.mol | [Molecular Weight]
395.45 |
| Hazard Information | Back Directory | [Description]
BRD-IN-3 ((R,R)-36n) is a highly potent PCAF bromodomain (BRD) inhibitor, with an IC50 of 7 nM. BRD-IN-3 also exhibits activity against GCN5 and FALZ[1].
IC50: PCAF BRD[1]. | [storage]
Store at -20°C | [References]
[1]. Huang L, et al. Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain. J Med Chem. 2019 May 9;62(9):4526-4542. |
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