| Identification | Back Directory | [Name]
Benzoic acid, 5-chloro-2-[[2-[2-[[3-(3-furanyl)phenyl]amino]-2-oxoethoxy]acetyl]amino]-, sodium salt (1:1) | [CAS]
2319722-53-5 | [Synonyms]
Benzoic acid, 5-chloro-2-[[2-[2-[[3-(3-furanyl)phenyl]amino]-2-oxoethoxy]acetyl]amino]-, sodium salt (1:1) | [Molecular Formula]
C21H18ClN2NaO6 | [MOL File]
2319722-53-5.mol | [Molecular Weight]
452.82 |
| Hazard Information | Back Directory | [Biological Activity]
TM 5441 is a plasminogen activator inhibitor-1 (PAI-1) inhibitor (IC50 = 3.58 - 60.3 μM). Increases apoptosis in human cancer cell lines. Reduces senescence and increases lifespan in mouse models of ageing (kl/kl). Inhibits L-NAME induced systolic blood pressure increases, telomere length reduction and cardiac hypertrophy in mice. Renoprotective. Orally bioavailable. | [storage]
Store at +4°C |
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