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AS-1763 is a potent, selective, noncovalent, and orally available inhibitor of Bruton’s tyrosine kinase (IC50 = 0.85 nM). | [References]
[1]. Kawahata W, et al. Discovery of AS-1763: A Potent, Selective, Noncovalent, and Orally Available Inhibitor of Bruton’s Tyrosine Kinase. J Med Chem. 2021 Oct 14;64(19):14129-14141. |
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