| Identification | Back Directory | [Name]
NS3861 >=98% (HPLC) | [CAS]
216853-59-7 | [Synonyms]
NS3861 >=98% (HPLC)
8-Azabicyclo[3.2.1]oct-2-ene, 3-(3-bromo-2-thienyl)-8-methyl-
α3β4 nAChR,inhibit,NS 3861,Inhibitor,NS3861,Heteromeric,Patch Clamp,Nicotinic acetylcholine receptors,nAChR,NS-3861,Pharmacology | [Molecular Formula]
C12H14BrNS | [MDL Number]
MFCD30182246 | [MOL File]
216853-59-7.mol | [Molecular Weight]
284.22 |
| Chemical Properties | Back Directory | [Boiling point ]
358.5±42.0 °C(Predicted) | [density ]
1.456±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: 2mg/mL, clear | [form ]
Solid | [pka]
8.26±0.40(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Biological Activity]
NS3861 is a neuronal nicotinic receptor agonist th at selectively activates α3 containing nAChRs and it displays higher efficacy at the α3β2 receptor compared with the α3β4 receptor. NS3861 does not activate α4 containing receptors. NS3861 was reported to reverse chronic opioid-induced constipation in vivo. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
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| Tel: |
|
| Website: |
www.sangon.com |
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
www.biorbyt.com |
|