午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

ChemicalBook--->CAS DataBase List--->209986-17-4

209986-17-4

209986-17-4 Structure

209986-17-4 Structure
IdentificationBack Directory
[Name]

γ-Secretase Inhibitor XXI
[CAS]

209986-17-4
[Synonyms]

DuPont E
γ-Secretase Inhibitor BZ
γ-Secretase Inhibitor BZ
g-Secretase Inhibitor XXI
γ-Secretase Inhibitor XXI
CoMpound E (secretase inhibitor)
BZ, γ-Secretase Inhibitor - Compound E
Compound E (γ-Secretase Inhibitor XXI)
StemSelect Compound E - CAS 209986-17-4 - Calbiochem
(S)-2-(2-(3,5-difluorophenyl)acetamido)-N-((S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanamide
(S)-2-(2-(3,5-difluorophenyl)acetamido)-N-((S,Z)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)propanamide
N-[(1S)-2-[[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
Benzeneacetamide, N-[(1S)-2-[[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-
[Molecular Formula]

C27H24F2N4O3
[MOL File]

209986-17-4.mol
[Molecular Weight]

490.5
Chemical PropertiesBack Directory
[Boiling point ]

778.6±60.0 °C(Predicted)
[density ]

1.31
[storage temp. ]

= -70C
[solubility ]

Soluble in DMSO
[form ]

Liquid
[pka]

12.54±0.40(Predicted)
[color ]

White to off-white
[Sensitive ]

Light Sensitive
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

A cell-permeable, potent, selective, peptidomimetic, non-transition-state analog inhibitor of -secretase and Notch processing
[Definition]

ChEBI: Compound E is an L-alanine derivative that is the amide obtained by formal condensation of the carboxy group of N-[(3,5-difluorophenyl)acetyl]-L-alanine with the amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one. An inhibitor of memapsin 2 (gamma-secretase). It has a role as an EC 3.4.23.46 (memapsin 2) inhibitor. It is a 1,4-benzodiazepinone, a L-alanine derivative and a difluorobenzene.
[Biological Activity]

Cell permeable: yes''Primary Target
γ-secretase and Notch processing Ab40 in CHO cells overexpressing wild type bAPP''Product does not compete with ATP.''Reversible: no''Target IC50: 300 pM for Aβ40 in CHO cells overexpressing wild typeβAPP; 240 pM for Aβ40370 pM for Aβ42and 320 pM for NICDrespectivelyin HEK293 cells stably transfected with βAPP695 and mNotchΔE(M1727V); 100 pM for both Aβ40
[storage]

+4°C
209986-17-4 suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Website: www.atkchemical.com
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471 , +1-2135480471
Website: https://www.sarms4muscle.com
Company Name: Nextpeptide Inc
Tel: +86-0571-81612335 +8613336028439 , +8613336028439
Website: http://www.nextpeptide.com/
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105 , +1-13798911105
Website: https://www.invivochem.com/
Company Name: LEAP CHEM CO., LTD.
Tel: +86-852-30606658
Website: www.leapchem.com
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
Tel: +undefined18051384581 , +undefined18051384581
Website: https://www.chemhifuture.com/
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Website: www.aladdinsci.com/
Company Name: VDM Biochemicals   
Tel: 0330-2528181
Website: www.vdmbio.com
Company Name: Shanghai Witofly Chemical Co.,Ltd  
Tel:
Website: www.witofly.com
Company Name: Shanghai SunSyn Pharmaceutical Co., Ltd.  
Tel: -2408801818 18621020637
Website: http://www.sunsynpharma.com
Company Name: ChemStrong Scientific Co.,Ltd  
Tel: 0755-0755-66853366 13670046396
Website: www.chem-strong.com
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Tel: 021-52996696,15000506266 15000506266
Website: http://www.bioll.com
Company Name: ShangHai Angti Biotechnology Co., Ltd.  
Tel: 13764913901
Website: http://www.angtibio.com
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: ShangHai Biochempartner Co.,Ltd  
Tel: 17754423994 17754423994
Website: https://www.biochempartner.com
Company Name: Shanghai Rechem science Co., Ltd.  
Tel: 21-31433387 15618786686
Website: cn.rechemscience.com
Company Name: Alabiotech Inc.  
Tel: 001-619-354-5251
Website: www.alabiotech-e.com
Tags:209986-17-4 Related Product Information
797035-11-1 208255-51-0 133407-83-7 209984-56-5 63-74-1 110-30-5 121660-11-5 208255-80-5

This site uses cookies
This website uses cookies and similar technologies to store and retrieve information about your use of this website. This information helps us to provide, analyse and improve our services, which may include personalised content or advertising. We may share this information with Google and other third parties. This cookies are necessary for our website to work properly . By clicking "Continue" or continuing to browse our site you are agreeing to our and our partners use of cookies.
Accept