Identification | Back Directory | [Name]
AcotiaMide | [CAS]
185106-16-5 | [Synonyms]
Acofide AcotiaMide ACOTIAMIDUM 185106-16-5 Acotiamide D4 YM443 free base Z-338 free base Acotiamide formate salt N-{2-[bis(1-methylethyl)amino]ethyl}-2-{[(2-hydroxy-4,5-dime... N-[2-[Bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxamide N-(2-(diisopropylamino)ethyl)-2-(2-hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxamide hydrochloride 4-Thiazolecarboxamide, N-[2-[bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]- N-{2-[bis(1-methylethyl)amino]ethyl}-2-{[(2-hydroxy-4,5-dimethoxyphenyl)carbonyl]amino}-1,3-thiazole-4-carboxamide Acotiamide D6Q: What is
Acotiamide D6 Q: What is the CAS Number of
Acotiamide D6 Q: What is the storage condition of
Acotiamide D6 Q: What are the applications of
Acotiamide D6 | [Molecular Formula]
C21H30N4O5S | [MDL Number]
MFCD00953661 | [MOL File]
185106-16-5.mol | [Molecular Weight]
450.552 |
Chemical Properties | Back Directory | [density ]
1.246±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
powder | [pka]
7.38±0.50(Predicted) | [color ]
white to beige | [Water Solubility ]
H2O: 20mg/mL, clear |
Hazard Information | Back Directory | [Definition]
ChEBI: Acotiamide is a member of salicylamides. | [Biological Activity]
Acotiamide is a potentselective and reversible inhibitor of human and canine stomach-derived acetylcholinesterase (AChE). Acotiamide showed no affinity for dopamine D2 or serotonin 5-HT4 receptors but does have activity as a muscarinic antagonist. It acts as a prokinetic drug through acetylcholinesterase inhibition and muscarinic receptor antagonismand has been used for the treatment of functional dyspepsia (FD) involving gastric motility dysfunction. |
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