| Identification | Back Directory | [Name]
TEZOSENTAN | [CAS]
180384-57-0 | [Synonyms]
TEZOSENTAN
N-(2-(2-(2H-Tetrazol-5-yl)pyridin-4-yl)-6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)pyrimidin-4-yl
N-(2-(2-(2H-Tetrazol-5-yl)pyridin-4-yl)-6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)pyrimidin-4-yl)-5
N-(2-(2-(2H-Tetrazol-5-yl)pyridin-4-yl)-6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)pyrimidin-4-yl)-5-isopropylpyridine-2-sulfonamide
N-[6-(2-Hydroxyethoxy)-5-(2-Methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]-4-pyriMidinyl]-5-(1-Methylethyl)-2-pyridinesulfonaMide | [Molecular Formula]
C27H27N9O6S | [MDL Number]
MFCD00949625 | [MOL File]
180384-57-0.mol | [Molecular Weight]
605.62 |
| Chemical Properties | Back Directory | [Melting point ]
198-200° | [Boiling point ]
761.2±70.0 °C(Predicted) | [density ]
1.432±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
2.93±0.10(Predicted) | [color ]
Off-white to gray |
| Hazard Information | Back Directory | [Uses]
A potent dual endothelian (ETA/ETB) receptor antagonist optimized from Bosentan (B675900). Tezosentan is used in the treatment of congestive heart failure.
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SPIRO PHARMA
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BOC Sciences
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Energy Chemical
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