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ChemicalBook--->CAS DataBase List--->16980-89-5

16980-89-5

16980-89-5 Structure

16980-89-5 Structure
IdentificationBack Directory
[Name]

Bucladesine
[CAS]

16980-89-5
[Synonyms]

DC 2797
,5Õ
DBcAMP-Na
N6-2Õ
Prestwick_32
CAMP, DB-, NA
BUCLADESINE NA
DIB-3:5-CAMP, NA
dt5621sodiumsalt
DIBUTYRYL-CAMP NA
bucladesinesodium
Sodium bucladesine
Dibutyacyladenosine
DIBUTYRYL-CYCLICAMP
sodiumdibutyrylcamp
DB-CAMP SODIUM SALT
BucladesineSodiumSal
Dibutyryl-cAMP, sodi
Bucladesine USP/EP/BP
dibutylcampsodiumsalt
dibutylcyclicampsodium
BUCLADESINE SODIUM SALT
ibutyryl cyclic AMP sodium
dibutylcyclicampsodiumsalt
Dibutyryl cyclic AMP sodium
DIBUTYRYL-CAMP, SODIUM SALT
monosodiumdibutyrylcyclicamp
Dibutyryl-cAMP (Bucladesine)
N6,2′-O-Dibutyryladenosine 3′
sodiumdibutyryl3’,5’-cyclicamp
-O-Dibutyryl-adenosine 3Õ
e,butyrate(ester),monosodiumsalt
DIBUTYRYL CYCLIC AMP SODIUM SALT
Dibutyacyladenosine cyclphosphate
Dibutyryl-cAMP sodium salt, >=98%
N6,2'-O-dibutyryl cAMP sodium salt
Dibutyryl-cAMP (Bucladesine sodium)
Bucladesine, Dibutyryl cyclic-AMP
Dibutyryl cyclic AMP monosodium salt
Dibutyryl 3',5'-cyclic AMP sodium salt
-cyclophosphate sodium salt monohydrate
N6.2-O-dibutyryladenosine-3.5-cyclic(+4℃)
Sodium dibutyryl adenosine cyclophosphate
Adenosine 3?,5?-cyclic Monophosphate, N?,O
Calcium Dibutyacyladenosine Cyclophosphate
N6,O2'-Dibutyryl-3',5'-cyclic AMP sodium salt
N6,2'-O-Dibutyryl-3',5'-cyclic AMP sodium salt
N6,2'-O-DIBUTYRYLADENOSINE 3':5'-CYCLIC MONOPHOSPHA
4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv.
N6,O2-DIBUTYRYLADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE NA
Sodium N6,2'-O-dibutyryladenosine 3',5'-cyclic phosphate
N6,O2'-DIBUTYRYLADENOSINE-3':5'-PHOSPHATE CYCLIC NA-SALT
N6,2'-O-DIBUTYRYLADENOSINE-3',5'-CYCLO-P HOSPHATE SO-SALT
N,2'-O-Dibutyryladenosine-3',5'-phosphoric acid sodium salt
n6,02’-dibutyryladenosine3’,5’-cyclicmonophosphatesodiumsalt
N6,O2'-DIBUTYRYLADENOSINE-3',5'-PHOSPHATE CYCLIC SODIUM SALT
2'-O-Dibutyryladenosine 3',5'-cyclic Monophosphate sodiuM salt
N,2'-O-Dibutanoyladenosine 3',5'-(phosphoric acid sodium) salt
N6,2'-O-Dibutyryladenosine-3',5'-monophosphate monosodium salt
N6,2'-O-DIBUTRYL-ADENISINE-3',5'-CYCLICMONPHOSPHATE SODIUM SALT
N6, O2-DIBUTYRYLADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE SODIUM SALT
N6,2'-O-Dibutyryladenosine3',5'-CyclicMonophosphateSodiumSalt>
N6,O2'-DIBUTYRYL ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
N6,2'-O-DIBUTYRYLADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
N6,2'-O-DIBUTYRYLADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
N-6,O-2'-Dibutyryladenosine cyclic 3',5'-monophosphate sodium salt
N6,2'-O-DIBUTYRYLADENOSINE-3':5'-CYCLIC MONOPHOSPHORIC ACID, SODIUM
ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, N6,O2'-DIBUTYRYL-, SODIUM SALT
dc2797 , sodium dibutyryl camp , dibutyryl-camp sodium salt , dbcamp
N6, 2'-O-Dibutyryadenosine 3',5'-cyclic monophosphate sodium salt, 96%
BUCLADESINE[N-6,O-2''-DIBUTYRYL ADENOSINE CYCLIC 3'',5''-MONOPHOSPHATE]
n6,2’-o-dibutyryladenosine-3’,5’-cyclicmonophosphate(dbcamp),sodiumsalt
n-(9-beta-d-ribofuranosyl-9h-purin-6-yl)-butyramidcyclichydrogenphosphat
ADENOSINE-3',5'-CYCLIC MONOPHOSPHORIC ACID, N,2'O-DIBUTYRYL, SODIUM SALT
adenosine,n-(1-oxobutyl)-,cyclic3’,5’-(hydrogenphosphate)-2’-butanoate,m
Adenosine,N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate,
N6,2'-O-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt, ≥97% (HPLC)
N-(1-Oxobutyl)adenosine cyclic 3',5'-(hydrogen phosphate)2'-butanoate sodium salt
N6,2μ-O-Dibutyryladenosine 3μ,5μ-cyclic monophosphate monohydrate sodium salt
Bucladesine Sodium Salt / Dibutyryl Adenosine Cyclophosphate Sodium Salt(DB-cAMP. Na)
Adenosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, monosodium salt
Adenosine,N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate, sodiuM salt(1:1)
Adenosine 3,5-cyclic Monophosphate, N,O2-Dibutyryl-, Sodium Salt - CAS 16980-89-5 - Calbiochem
Bucladesine sodium salt, Dibutyryl cAMP sodium salt, Dibutyryl cyclic-AMP sodium salt
butyramide,n-(9-beta-d-ribofuranosyl-9h-purin-6-yl)-,cyclichydrogenphosphate,butyrate(ester),monosodiumsalt
Butyramide, N-(9-b-D-ribofuranosyl-9H-purin-6-yl)-, cyclic hydrogen phosphate butyrate (ester), monosodium salt (8CI)
[EINECS(EC#)]

241-059-4
[Molecular Formula]

C18H23N5NaO8P
[MDL Number]

MFCD00005843
[MOL File]

16980-89-5.mol
[Molecular Weight]

491.37
Chemical PropertiesBack Directory
[Melting point ]

>173°C (dec.)
[storage temp. ]

−20°C
[solubility ]

H2O: 50 mg/mL
[form ]

powder
[color ]

white
[Merck ]

14,1463
[Stability:]

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
Safety DataBack Directory
[Safety Statements ]

24/25
[WGK Germany ]

2
[RTECS ]

ES5055500
[F ]

10-21
[HS Code ]

29349990
Hazard InformationBack Directory
[Description]

Bucladesine sodium is a derivative of cyclic-AMP with cardiac stimulant and peripheral vasodilatory properties. It is reported to be useful in cardiac insufficiency, especially after heart surgery.
[Originator]

Daiichi Seiyaku; Seishin Seiyaku (Japan)
[Uses]

An analog of cyclic AMP that stimulates cAMP-dependent protein kinase
[Uses]

Cardiotonic;Adenylate cyclase modulator
[Application]

N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt has been used:
as a medium supplement for neural crest stem cells (NCSCs) differentiation
as a component of thawing medium for cryopreserved human iPSC (induced pluripotent stem cell)-derived neurons
in serum-free Dulbecco′s modified eagle′s medium (DMEM) to induce astrocyte differentiation
[Definition]

ChEBI: Bucladesine sodium is a 3',5'-cyclic purine nucleotide.
[Brand name]

ACTOCIN
[General Description]

A cell-permeable cAMP analog that preferentially activates cAMP-dependent protein kinase (PKA). Causes an increase in the steady state level of parathyroid hormone-related peptide mRNA. Also acts as a Hh pathway antagonist. Shown to induce apoptosis in vascular smooth muscle cells.
[Biological Activity]

Cell-permeable analog of cAMP; activates cAMP-dependent protein kinases.
[Biochem/physiol Actions]

Cell-permeable cAMP analog that activates cAMP dependent protein kinase (PKA).
[storage]

Store at -20°C
[References]

1) Bartsch?et al.?(2003),?Bioactivatable, membrane-permeant analogs of cyclic nucleotides as biological tools for growth control of C6 glioma cells; Biol. Chem.,?384?1321 2) Carranza?et al.?(1998),?Protein kinase A induces recruitment of active Na+,K+-ATPase units to the plasma membrane of rat proximal convoluted tubule cells; J. Physiol.,?15?511 3) Hei?et al.?(1991),?Lack of correlation between activation of cyclic AMP-dependent protein kinase and inhibition of contraction of rat vas deferens by cyclic AMP analogs; Mol. Pharmacol.,?39?233 4) Imamura?et al.?(1998),?Differential expression of dystrophin isoforms and utrophin during dibutyryl-cAMP-induced morphological differentiation of rat brain astrocytes; Proc. Natl. Acad. Sci. USA,?95?6139 5) Xia?et al.?(2016),?Transcriptional comparison of human induced and primary midbrain dopaminergic neurons; Sci. Rep.,?6?20270
Spectrum DetailBack Directory
[Spectrum Detail]

Bucladesine sodium(16980-89-5)1HNMR
Bucladesine sodium(16980-89-5)IR1
Bucladesine sodium(16980-89-5)IR2
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