| Identification | Back Directory | [Name]
SB 205384 | [CAS]
160296-13-9 | [Synonyms]
SB 205384
SB 205384 solid
4-Amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-(1H)benzothieno[2,3-b]pyridine-3-carboxylicacid2-butynylester
4-AMINO-7-HYDROXY-2-METHYL-5,6,7,8-TETRAHYDROBENZO[B]THIENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID BUT-2-YNYL ESTER
4-Amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydrobenzo[b]thieno[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester
4-AMINO-5,6,7,8-TETRAHYDRO-7-HYDROXY-2-METHYL-[1H]BENZOTHIENO[2,3-B]PYRIDINE-3-CARBOXYLIC ACID 2-BUTYNYL ESTER
[1]Benzothieno[2,3-b]pyridine-3-carboxylic acid, 4-amino-5,6,7,8-tetrahydro-7-hydroxy-2-methyl-, 2-butyn-1-yl ester | [Molecular Formula]
C17H18N2O3S | [MDL Number]
MFCD00918851 | [MOL File]
160296-13-9.mol | [Molecular Weight]
330.4 |
| Chemical Properties | Back Directory | [Boiling point ]
565.3±50.0 °C(Predicted) | [density ]
1.380±0.06 g/cm3(Predicted) | [storage temp. ]
Desiccate at RT | [solubility ]
DMSO: 18 mg/mL | [form ]
solid | [pka]
14.28±0.20(Predicted) | [color ]
off-white |
| Hazard Information | Back Directory | [Uses]
SB 205384 is a GABAA modulator with a novel mechanism of action that shows subunit selectivity. | [Definition]
ChEBI: 4-amino-7-hydroxy-2-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-b]pyridine-3-carboxylic acid but-2-ynyl ester is a thienopyridine. | [Biological Activity]
GABA A receptor modulator; slows current decay. Displays some specificity for α 3-subunit-containing receptors (in particular α 3 β 2 γ 2), having little effect on receptors containing α 1 or α 2 subunits. |
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Energy Chemical
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Merck KGaA
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