| Identification | Back Directory | [Name]
11(S)-HEPE | [CAS]
156473-26-6 | [Synonyms]
11(S)-HEPE
IDEHSDHMEMMYIR-HODZVVMCSA-N
11S-HYDROXY-5Z,8Z,12E,14Z,17Z-EICOSAPENTAENOIC ACID
5,8,12,14,17-Eicosapentaenoic acid, 11-hydroxy-, [S-(E,Z,Z,Z,Z)]- (9CI) | [Molecular Formula]
C20H30O3 | [MDL Number]
MFCD00065815 | [MOL File]
156473-26-6.mol | [Molecular Weight]
318.45 |
| Chemical Properties | Back Directory | [Boiling point ]
488.0±45.0 °C(Predicted) | [density ]
0.997±0.06 g/cm3(Predicted) | [solubility ]
0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml | [pka]
4.75±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
11(S)-HEPE is a monohydroxy fatty acid derived from EPA, theoretically by the action of COX. Although its arachidonate derived congener 11(S)-HETE has been isolated from cultured neutrophils, it is not known if similar incubations with EPA can produce 11(S)-HEPE.1 | [Uses]
11(S)-HEPE is a monohydroxy fatty acid derived from EPA (eicosapentaenoic acid)[1]. | [Definition]
ChEBI: 11S-HEPE is a HEPE. | [References]
1. Myers, R.F., and Siege, M.I. Differential effects of anti-inflammatory drugs in lipoxygenase and cyclo-oxygenase activities of neutrophils from a reverse passive arthus reaction Biochem. Biophys. Res. Commun. 112,586-594(1983). |
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