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ChemicalBook--->CAS DataBase List--->154554-41-3

154554-41-3

154554-41-3 Structure

154554-41-3 Structure
IdentificationBack Directory
[Name]

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158
[CAS]

154554-41-3
[Synonyms]

CHM 1
NSC 656158
CHM-1 hydrate
6-(2-Fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5H)-one
6-(2-Fluoro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-8-one
1,3-Dioxolo[4,5-g]quinolin-8(5H)-one, 6-(2-fluorophenyl)-
2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate
2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158
Inhibitor,microtubule-destabilizing,Cdc2,carcinoma,CHM1,NSC-656158,Microtubule/Tubulin,hepatocellular,NSC656158,antitumor,inhibit,CHM-1,CHM 1,antimitotic,NSC 656158
[Molecular Formula]

C16H10FNO3
[MDL Number]

MFCD11114577
[MOL File]

154554-41-3.mol
[Molecular Weight]

283.25
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: ≥5mg/mL
[form ]

solid
[color ]

Off-white to light yellow
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

CHM-1 is a potent apoptosis inducer.
[Biological Activity]

CHM-1 possess antimitotic,antiangiogenic and antitumor activity. It is a potent and selective antitumor agent in human hepatocellular carcinoma. CHM-1 induces apoptosisand it binds tubulin and inhibits tubulin polymerization.
Spectrum DetailBack Directory
[Spectrum Detail]

2-(2-fluorophenyl)-6,7-methylenedioxy-2-4-quinolone hydrate, NSC 656158(154554-41-3)1HNMR
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