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ChemicalBook--->CAS DataBase List--->146998-34-7

146998-34-7

146998-34-7 Structure

146998-34-7 Structure
IdentificationBack Directory
[Name]

S15535
[CAS]

146998-34-7
[Synonyms]

S15535 >=98% (HPLC), solid
4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine
1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-4-(2,3-dihydro-1H-inden-2-yl)piperazin
Piperazine,1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-(2,3-dihydro-1H-inden-2-yl)-
[Molecular Formula]

C21H24N2O2
[MDL Number]

MFCD00911672
[MOL File]

146998-34-7.mol
[Molecular Weight]

336.43
Chemical PropertiesBack Directory
[Boiling point ]

504.5±50.0 °C(Predicted)
[density ]

1.228±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: ~6 mg/mL
[form ]

solid
[pka]

7.84±0.70(Predicted)
[color ]

white
Safety DataBack Directory
[Hazard Codes ]

N
[Risk Statements ]

50
[Safety Statements ]

61
[RIDADR ]

UN 3077 9/PG 3
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

S15535 has been used as a serotonin 1A receptor (5-HT1A) agonist in zebrafish.', 'S15535 may be used in histamine 5-HT1A-medaited cell signaling studies.
[Biological Activity]

S15535a benzodioxaneis a selective but partial agonist of histamine serotonin 1A (5-HT1A) receptor. It activates presynaptic 5-HT1A receptors and suppresses the release of hippocampal 5-HT. It acts as an anxiolytic agent and modulates the cholinergic and cognitive function in rodents.''Potentorally activepartial 5-HT1A receptor agonist
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