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ChemicalBook--->CAS DataBase List--->145731-49-3

145731-49-3

145731-49-3 Structure

145731-49-3 Structure
IdentificationBack Directory
[Name]

CALPAIN INHIBITOR XI
[CAS]

145731-49-3
[Synonyms]

CALPAIN INHIBITOR XI
TZVQRMYLYQNBOA-UHFFFAOYSA-N
Z-L-ABU-CONH(CH2)3-MORPHOLINE
Carbamic acid, [1-[[[1-ethyl-3-[[3-(4-morpholinyl)propyl]amino]-2,3-dioxopropyl]amino]carbonyl]-3-methylbutyl]-, phenylmethyl ester (9CI)
[Molecular Formula]

C26H40N4O6
[MDL Number]

MFCD06411394
[MOL File]

145731-49-3.mol
[Molecular Weight]

504.62
Chemical PropertiesBack Directory
[density ]

1.145±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO: 5mg/mL
[form ]

Solid
[pka]

11.10±0.46(Predicted)
[color ]

white to off-white
[Sensitive ]

Light Sensitive
Hazard InformationBack Directory
[Uses]

A cell-permeable dipeptidyl -ketoamide that acts as a potent, highly selective, reversible, and active site inhibitor of calpain-1 and -2
[Biological Activity]

Cell permeable: yes''Primary Target
calpain 1calpain 2''Product does not compete with ATP.''Reversible: yes''Target Ki: 140 nM and 41 nMagainst calpain-1 and -2respectively
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