Identification | Back Directory | [Name]
L-Prolinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- | [CAS]
1448189-66-9 | [Synonyms]
JYS002 L-Prolinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- | [Molecular Formula]
C26H36N4O5S | [MOL File]
1448189-66-9.mol | [Molecular Weight]
516.65 |
Hazard Information | Back Directory | [Uses]
VH032 analogue-2 is a VH032 (HY-120217) analog that acts as a ligand for VHL, recruiting von Hippel-Lindau (VHL) protein. VH032 analogue-2 will remove the protective group under acidic conditions, and can be directly used for the synthesis of PROTAC molecules. VH032 analogue-2 is a key intermediate for the synthesis of PROTACs based on VHL ligands. | [IC 50]
VHL |
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