| Identification | Back Directory | [Name]
FTY720-d4 Hydrochloride | [CAS]
1346604-90-7 | [Synonyms]
Fingolimod-d4 HCl
[2H4]-Fingolimod HCl
FTY720-d4 Hydrochloride
FingoliMod-d4 Hydrochloride
[2H4]-Fingolimod Hydrochloride
Fingolimod-d4 HCl (1,3-propane-1,1,3,3-d4-diol)
2-AMino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol-d4 Hydrochloride
2-amino-1,1,3,3-tetradeuterio-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol | [Molecular Formula]
C19H34ClNO2 | [MDL Number]
MFCD32858129 | [MOL File]
1346604-90-7.mol | [Molecular Weight]
343.932 |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
A labelled derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively). | [Uses]
A labelled derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. t is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively). | [storage]
Store at -20°C |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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