| Identification | Back Directory | [Name]
R-(a’)-7-Desmethyl-8-nitro Blebbistatin | [CAS]
1217619-62-9 | [Synonyms]
(R)-nitro-Blebbistatin
R-()-7-Desmethyl-8-nitro Blebbistatin
R-(a’)-7-Desmethyl-8-nitro Blebbistatin
4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-7-nitro-1-phenyl-, (3aR)- | [Molecular Formula]
C17H13N3O4 | [MOL File]
1217619-62-9.mol | [Molecular Weight]
323.3 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 20 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml | [form ]
A crystalline solid |
| Hazard Information | Back Directory | [Uses]
R-(?)-7-Desmethyl-8-nitro Blebbistatin is a metabolite of (+/-)-Blebbistatin (B592490), a selective inhibitor of nonmuscle myosin II; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells. |
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