| Identification | Back Directory | [Name]
Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid) | [CAS]
1206695-46-6 | [Synonyms]
Fesoterodine L-mandelate
Fesoterodine ((S)-2-hydroxy-2-phenylacetic acid)
2-[(1R)-3-[bis(1-methylethyl)amino]-1-phenylpropyl]-4-hydroxy-methylphenyl isobutyrate mandelate | [Molecular Formula]
C34H45NO6 | [MDL Number]
MFCD28167924 | [MOL File]
1206695-46-6.mol | [Molecular Weight]
563.724 |
| Hazard Information | Back Directory | [Uses]
Fesoterodine ((S)-2-Hydroxy-2-phenylacetic Acid) is a salt of Fesoterodine, an antimuscarinic prodrug for the treatment of overactive bladder syndrome. | [in vivo]
Fesoterodine L-mandelate (0.01-1 mg/kg; IV) reduces the micturition pressure and increases bladder capacity and ICIs (intercontraction intervas) at the lowest dose tested of 0.01 mg/kg[3]. | Animal Model: | Bladders from female Sprague-Dawley rats (225-275 g)[3] | | Dosage: | 0.01, 0.1 and 1 mg/kg | | Administration: | IV | | Result: | Reduced the micturition pressure and increased bladder capacity and ICIs at the lowest dose tested of 0.01 mg/kg.
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| [IC 50]
mAChR1; mAChR3; mAChR4; mAChR5 |
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