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ChemicalBook--->CAS DataBase List--->1133766-06-9

1133766-06-9

1133766-06-9 Structure

1133766-06-9 Structure
IdentificationBack Directory
[Name]

Onartuzumab
[CAS]

1133766-06-9
[Synonyms]

Onartuzumab
Onartuzumab (anti-MET)
Research Grade Onartuzumab (DHC34202)
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Description]

Onartuzumab is a monoclonal antibody that blocks the binding of HGF to the MET receptor.
[Clinical Use]

Onartuzumab is ineffective in improving clinical outcomes in (i) combination with current first-line chemotherapy in advanced nonsquamous cell NSCLC , (ii) combination with erlotinib in previously treated stage IIIB or IV NSCLC patients (Phase III) , and (iii) combination with platinum-doublet chemotherapy in advanced squamous cell NSCLC (Phase II) .
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