| Identification | Back Directory | [Name]
D(+)-VESAMICOL HYDROCHLORIDE | [CAS]
112709-60-1 | [Synonyms]
D(+)-VESAMICOL HCL
1s-trans-cyclohexano
D(+)-VESAMICOL HYDROCHLORIDE
(1S,2S)-2-(4-Phenyl-1-piperidinyl)cyclohexanol
Cyclohexanol, 2-(4-phenyl-1-piperidinyl)-, (1S,2S)- | [Molecular Formula]
C17H25NO | [MDL Number]
MFCD00069370 | [MOL File]
112709-60-1.mol | [Molecular Weight]
259.39 |
| Chemical Properties | Back Directory | [Boiling point ]
393.5±42.0 °C(Predicted) | [density ]
1.086±0.06 g/cm3(Predicted) | [solubility ]
DMSO: soluble | [form ]
solid | [pka]
15.16±0.40(Predicted) | [color ]
white |
| Hazard Information | Back Directory | [Uses]
D-(+)-Vesamicol hydrochloride can be used as a reactant to prepare:
- Trialkylstannyl vesamicol analogs as potent vesicular acetylcholine transporters (VAChTs) and sigma receptors.
- Vesamicol analog, (+)-2-[4-(4-iodophenyl)piperidino] cyclohexanol as a possible tumor imaging agent.
| [General Description]
D-(+)-Vesamicol is a potent inhibitor of acetycholine transport into the synaptic vesicles in cholinergic nerve terminals. It is 25-times less potent than the L-form. | [Biochem/physiol Actions]
Less active enantiomer of vesamicol |
|
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