| Identification | Back Directory | [Name]
2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE | [CAS]
109740-09-2 | [Synonyms]
CHEMBL241987
CHEMBL241987,CHEMBL-241987
2-phenyl-5H-pyrazolo[3,4-c]quinolin-4-one
2-Phenyl-2H,4H,5H-pyrazolo[3,4-c]quinolin-4-one
2-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-C]QUINOLIN-4-ONE | [Molecular Formula]
C16H11N3O | [MDL Number]
MFCD07339082 | [MOL File]
109740-09-2.mol | [Molecular Weight]
261.28 |
| Hazard Information | Back Directory | [Uses]
A3AR antagonist 4 (Compd 1) is an A3AR antagonist, with Ki values of 30.8 nM (hA3) and 203 nM (hA1), repectively. A3AR antagonist 4 (Compd 1) can be used for the study of cerebral ischemia[1]. | [References]
[1] Vittoria Colotta, et al. New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies. J Med Chem. 2007 Aug 23;50(17):4061-74. DOI:10.1021/jm070123v |
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