| Identification | Back Directory | [Name]
TGF-ALPHA | [CAS]
105186-99-0 | [Synonyms]
ETGF
TGF-α
hTGF-α
TGF-ALPHA
TGF-TYPE I
TGF type 1
HUMAN TGF-A
RHTGF-ALPHA
TGF-A, HUMAN
EGF-like TGF
RAT TGF-ALPHA
TGF-ALPHA, RAT
HUMAN TGF-ALPHA
TGF-ALPHA, HUMAN
TGF A (1-50) (RAT)
SARCOMA GROWTH FACTOR
TGF ALPHA (1-50) (RAT)
RECOMBINANT HUMAN TGF-A
TGF ALPHA (1-50) (HUMAN)
TGF-α, Human, Recombinant,
transforming growth factor-α human
TGF-α, Human, Recombinant, E. coli
transforming growth factor-A human
TRANSFORMING GROWTH FACTOR, ALPHA-
TGF-α, Transforming Growth Factor-α
TRANSFORMING GROWTH FACTOR-ALPHA RAT
TRANSFORMING GROWTH FACTOR-ALPHA HUMAN
HUMAN TRANSFORMING GROWTH FACTOR ALPHA
Transforming Growth Factor-a,Human, Recomb.
TRANSFORMING GROWTH FACTOR ALPHA (1-50) (RAT)
Anti-TGF α, C-Terminal antibody produced in rabbit
TRANSFORMING GROWTH FACTOR-A, HUMAN*RECO MBINANT, EX
TRANSFORMING GROWTH FACTOR-ALPHA, HUMAN, RECOMBINANT
H-VAL-VAL-SER-HIS-PHE-ASN-LYS-CYS-PRO-ASP-SER-HIS-THR-GLN-TYR-CYS-PHE-HIS-GLY-THR-CYS-ARG-PHE-LEU-VAL-GLN-GLU-GLU-LYS-PRO-ALA-CYS-VAL-CYS-HIS-SER-GLY-TYR-VAL-GLY-VAL-ARG-CYS-GLU-HIS-ALA-ASP-LEU-LEU-ALA-OH
VAL-VAL-SER-HIS-PHE-ASN-ASP-CYS-PRO-ASP-SER-HIS-THR-GLN-PHE-CYS-PHE-HIS-GLY-THR-CYS-ARG-PHE-LEU-VAL-GLN-GLU-ASP-LYS-PRO-ALA-CYS-VAL-CYS-HIS-SER-GLY-TYR-VAL-GLY-ALA-ARG-CYS-GLU-HIS-ALA-ASP-LEU-LEU-ALA HUMAN | [Molecular Formula]
C239H348N70O72S6 | [MDL Number]
MFCD00082077 | [MOL File]
105186-99-0.mol | [Molecular Weight]
5546.14 |
| Hazard Information | Back Directory | [Uses]
Transforming Growth Factor-α human has been used:
- to determine the ideal concentration of growth factors to be used in the culture medium that supports sheep preantral follicles
- in human hepatocytes cell culture and keratinocyte cell culture
- to induce morphogenesis in primary mouse organoids
| [General Description]
The TNFα (tumor necrosis factor α) gene is mapped to human chromosome 6p21.33. TNFα is a member of TNF superfamily. | [Biochem/physiol Actions]
The TNFA gene is significantly associated with the regulation of innate and adaptive immune responses. Polymorphism of TNFA gene is known to cause acute motor axonal neuropathy. The cytokine release and gene action is associated with epithelial cells, myeloid cells, endothelial, as well as tumor cells. Tumor cells are known to release TNFA, specifically in response to chemotherapy. |
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