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ChemicalBook--->CAS DataBase List--->102448-00-0

102448-00-0

102448-00-0 Structure

102448-00-0 Structure
IdentificationBack Directory
[Name]

dihydroxanthohumol
[CAS]

102448-00-0
[Synonyms]

dihydroxanthohumol
α,β-dihydroxanthohumol
[Molecular Formula]

C21H24O5
[MOL File]

102448-00-0.mol
[Molecular Weight]

356.41
Chemical PropertiesBack Directory
[Melting point ]

132 - 135oC
[storage temp. ]

-20°C, Inert atmosphere, Light sensitive
[solubility ]

Acetone (Slightly), Chloroform (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Stability:]

Light Sensitive
Hazard InformationBack Directory
[Uses]

Dihydroxanthohumol, >90% is a minor hop prenylflavonoid and a derivative of Xanthohumol (X741950). Unlike Xanthohumol, Dihydroxanthohumol cannot be metabolized to 8-Prenylnaringenin (P712900). Dihydroxanthohumol was shown to have antiproliferative activity against cancer cells.
[Definition]

ChEBI: Dihydroxanthohumol is a member of the class of dihydrochalcones that is the alpha,beta-dihydro derivative of xanthohumol. Isolated from Humulus lupulus, it exhibits inhibition of NO production. It has a role as a metabolite and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of dihydrochalcones, a polyphenol and an aromatic ether.
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